|
Research
SCITCS FES Research Laboratory
Click here to download
the research application form.
Additional
Information on FES Research at the University of Alberta
Dave Collins, PhD
Additional information on
Walking ...Again Research in AHFMR Research News (pages 16 and 17)
Download recent articles from SCITCS News
Engineering Research For
Spinal Cord Injury
Then
click here to run the video.
SEE Persons with SCI
using recumbent tricycles, arm-cranking systems for people with
quadriplegia and treadmill walking using partial body-weight
support.
Application
of FES at the University of Glasgow, Scotland.
Learn more about FES indoor competitive rowing in the UK.
Management of Chronic Pain in SCI Thomas E. Balazy, MD
Regaining bladder control NEW RESEARCH in 2006-2007
A technique pioneered in China by Dr.Chuan-Gao
Xiao at the Huazhong University of Science and Technology. Surgeons
cut open a spot on the spine and sew two normally unrelated nerves
together--one from the bladder to one from the thigh--with a single
hair-thin stitch. It takes months for this new nerve bridge to heal.
If it works, merely scratching the thigh should signal the bladder
to empty. To date 110 spinal cord injury patients and 230 with spina
bifida have undergone the procedure with an 80% success rate.
Vivian K. Mushahwar, PhD
Principal Investigator in Spinal Cord
Injury and Rehabilitation Engineering
- B.Sc. Electrical and Computer Engineering, Brigham Young
University, Provo, Utah, USA (1986 -1991)
- PhD Bioengineering, University of Utah, Salt Lake City, Utah,
USA (1992-1996)
- Post-doctoral Fellow in Rehabilitation Medicine, Emory
University, Atlanta, Georgia, USA (1996 - 1998)
- Post-doctoral Fellow in Physiology, University of Alberta,
Edmonton, Alberta, Canada (1998 - 2001)
- Assistant Professor, Department of Biomedical Engineering,
Faculty of Medicine and Dentistry (2001 - present)
- AHFMR Scholar (2002 present)
- Adjunct Assistant Professor, Department of Bioengineering,
University of Utah (2001 present)
- Adjunct Assistant Professor, Center for Neuroscience, University
of Alberta (2002 present)
- Adjunct Assistant Professor, Department of Physical Therapy,
Faculty of Rehabilitation Medicine, University of Alberta (2005
present)
The overall goal of the
work in my, "Spinal Cord Injury and Neuroprostheses"
, "Spinal Cord Injury Treatment Centre Functional Electrical
Stimulation Research" and the "Rehabilitation Engineering", laboratories is to develop
rehabilitation interventions for improving and restoring lost
function after spinal cord injury, head trauma or stroke. My
multidisciplinary research team is composed of biologists, engineers
and neuroscientists and we collaborate with multiple laboratories at
the University of Alberta and across North America. Our work is
funded by the Alberta Heritage Foundation for Medical Research (AHFMR),
the Canadian Fund for Innovation (CFI), the Canadian Institutes of
Health Research (CIHR), the International Spinal Cord Injury Trust (ISRT)
the Spinal Cord Injury Treatment Centre (Northern Alberta) Society
(SCITCS) and the United State National Institutes of Health (NIH).

Vivian K. Mushahwar PhD (Front R) with her multidisciplinary
research team.
On January 11th, 2006 the SCITCS
Board of Directors donated $80,123.56 to research the
development of deep pressure ulcer formation through the SCITCS Craig Simpson Quality of Life Research Grant.
The funds will be used to develop a method for preventing
the onset of deep ulcers using novel electrical stimulation paradigms.
See Research Project
number 3 below for additional information To participate in this
research phone 780 492-8480
Nine research projects are
currently underway in Dr. Mushawhar's three laboratories:
|
1) and 2) Restoring Standing and
Stepping after Spinal Cord Injury through the Use of Intraspinal
Microstimulation
The restoration of standing
and walking after spinal cord injury has the benefits of improving
muscle and skin properties, joint health and bone density, and
cardiovascular and pulmonary function. Intraspinal microstimulation
(ISMS) is a novel electrical stimulation technique that uses very
fine, hair-like wires to stimulate the "control center"
for standing and stepping in the spinal cord. The microwires are
implanted in a relatively small region of the cord (about 5 cm) and
patterned stimulation through these wires can generate coordinated
muscle contractions in the legs. These contractions produce balanced
standing and walking movements. This is a large project focused on
assessing the long-term functionality and benefits of ISMS and its
effects on muscle health.
Contact Lisa Guevremont
(PhD student) and Bernice Lau (Honors Electrical Engineering
Student)
|
 |
|
3) Early Detection and
Prevention of Deep Pressure Sores
Wheelchair-users and
bed-ridden individuals are at high risk of developing pressure
sores. Pressure sores can develop at the surface of the skin due to
multiple factors including abrasions, moisture and poor nutrition.
Sores can also develop from the inside-out as a result of deep
tissue necrosis (death) and can cause massive tissue damage prior to
exhibiting clear skin signs. The goals of this project are two fold:
developing tools that would allow for early detection of deep tissue
death and preventing the death of deep tissue by enhancing the
oxygenation level at high risk regions that are susceptible to
necrosis.
Contact Leandro Solis (PhD Student)
|
 |
|
4) Reduction of Spasticity
after Spinal Cord Injury and Stroke
Spasticity is a very
debilitating side-effect of spinal cord injury and stroke. It can
lead to uncontrolled spasms and compromise the efficiency of
residual voluntary function. This project focuses on obtaining a
better understanding of the mechanisms of spasticity using computer
modeling, and developing surface electrical stimulation and training
paradigms that would reduce spasticity in individuals with spinal
cord injury and stroke. Our aim is to achieve this reduction in
excitability without suppressing muscle facilitation.
Contact Sherif ElBasiouny
(PhD Student)
|
 |
|
5) Neuroprotection of the
Spinal Cord from the Deleterious Effects of Secondary Injury
Immediately following
spinal cord injury, a cascade of harmful chemical reactions take
place around the injured tissue that result in the expansion of the
injured site and the loss of additional neural tissue. This cascade
is referred to as secondary injury and commonly leads to increasing
the magnitude of functional loss cause by the initial (or primary)
injury. The goal of this project is to reduce the extent of
secondary injury by removing the harmful chemical byproducts around
the injury site and replacing them with fresh, nutrient-rich fluids.
The original concept for this project was developed in 2002 by Jan
Kowalczewski, a summer student in the lab.
Contact Andrew Ganton
(MSc Student)
|
 |
|
6) Non-invasive
Assessment of Spinal Cord Health after Injury and in response to
Rehabilitation Interventions
Treatment of spinal cord
injury requires proper assessment of spinal cord tissue in order to
determine the extent of injury and the biochemical composition of
the environment of the cord around the injury site. The goal of this
project is to develop non-invasive magnetic resonance imaging (MRI)
and spectroscopy (MRS) techniques that would allow for anatomical
and chemical assessment of spinal cord tissue. This information will
be used to determine the extent of injury, the time and mode of
intervention following injury, and the effect of various
conventional and novel rehabilitation treatments on spinal cord
health. Contact Daniel Hallihan
(MScStudent), Steven McGie (Honors Neuroscience Student)
|
 |
7) Rehabilitation of Limb Function
using Feedback-Based Training
A staggering 1.3% of all Canadians are
living with stroke, spinal cord injury, or Parkinson's disease, the
vast majority of whom have diminished arm function. Our goal is to
gain a greater understanding of the neural processes underlying
voluntary multi-joint reaching movements, and to develop operant
conditioning training protocols (i.e., biofeedback-based training)
to modify weak or pathological activity in the brain and spinal
cord.
CONTACT: Andrew Ganton (MSc Student)
8) Restoration of Limb Function after
Spinal Cord Injury using Functional Electrical Stimulation-Induced
Plasticity.
Loss of regulated sensory input from the limbs after spinal cord
injury further exaggerates the movement deficits resulting from the
injury itself. Sensory information from the arms and legs is
critical for shaping the activity patterns on the spinal networks
responsible for controlling limb movements. Our goal is to
develop FES training protocols to regulate the sensory input to the
spinal cord in order to improve arm and leg function, and to gain a
better understanding of the role sensory input and reflexes play in
controlling limb movements after injury.
CONTACT: Andrew Ganton (MSc Student)
9) Muscle Activation by Electrical
Stimulation in the Spinal Cord
Intraspinal microstimulation (ISMS) offers the potential to
generate movements that are fatigue resistant and to initiate force
production that is well controlled. This project evaluates the
muscle activation properties of ISMS by determining whether or not
this new technique can maintain chronically paralyzed muscle in a
healthy state.
CONTACT: Jeremy Bamford (PhD Student)
|